episode 1 of season 6.The two forensic teams come back together under the leadership of Grissom and Catherine just in time to tackle three separate investigations: a murdered couple found in bed in a suspicious trailer explosion; a beautiful stripper discovered dead and dumped in the worst part of town.

The team investigates when a young movie star is found dead in a hotel suite left in a compromising position. The movie star died after a night of heavy partying in his hotel suite along with his large band of groupies. Meanwhile, while downstairs at the hotel, the CSIs discover that the immigrant kitchen workers may have turned against each other, and their hostilities between one another may have led to murder.

When a woman meets her death on a flight of stairs, the team investigates and finds enough blood evidence to indicate that her death was not an accident.

When one cult member turns up missing at a mass suicide crime scene, Grissom and his team investigate whether the small cult really committed suicide or were murdered. A middle of the night break-in at a suburban home on the edge of the Vegas desert leads the CSIs to discover an abandoned military compound being used to house a small cult. Once inside, they discover a mass suicide has taken place. However, with 11 bodies and 12 beds, Grissom surmises that the killer may be the one body missing.

The CSI team suspects an entire family has been murdered, but cannot prove it until they find the victims’ bodies. When the blood evidence suggests only three people were killed, Nick is the only one on the CSI team that believes the fourth family member, the young daughter, is still alive. Now, it’s a race against time to find the perpetrators who may lead the CSIs to a possible survivor.

The CSIs uncover evidence that leads them to question whether or not a young mother’s death was really a suicide. The CSI team uncovers evidence in the investigation of a young mother’s suicide that proves that the woman’s newborn baby was not her biological child -- in fact, she was still technically a virgin at the time of her death. If the team discovers how the child was conceived, the answer may lead them to a killer. Meanwhile, Grissom is called into court to refute expert witness testimony from a suspected manipulator of evidence.

The CSI team investigates the death of a police officer during a wild Vegas shootout that may have been caused not by the criminals they were pursuing, but by one of his fellow officers. Part one of a two-part episode.

The CSIs sift through the overwhelming evidence from a shootout with drug dealers in order to determine who is responsible for the death of a police officer killed during the incident, on the conclusion of a two-part episode. When a wild police chase of drug smugglers through the streets of Las Vegas leaves an officer killed, the CSIs suspect that the cop killed in the line of duty was shot by one of his fellow officers.

The CSIs investigate the unusual death of a man found dead in a dumpster on Thanksgiving night. Grissom and his team must take their clues from what the man ate in order to identify his cause of death, which leads them into the world of competitive eating. Meanwhile, Nick and Sara investigate the suspicious death of a couple attacked and killed by their seemingly sweet dog.

The lack of evidence in a reported kidnapping case leads Grissom and his team to wonder if the case is fabricated. Without substantial evidence, the CSIs begin to wonder if a kidnapping actually took place at all. But when the child turns up unharmed at a local convenience store with a couple claiming to be his parents, Grissom and his team must use what little forensic evidence is available to solve the mystery of what actually happened to the first mother’s son.

The CSIs investigate the murder of a man who has Hypertrichosis, the human werewolf syndrome, which makes him grow excessive body hair. After further investigation, Stokes and Willows uncover a secret which ends up being the key to solving the crime.

Warrick, Sara, and Greg investigate the death of a young motocross racer whose girlfriend’s relationships have a tendency to end in tragedy. Meanwhile, Nick and Catherine investigate the death of a woman who was run over by a car. After fruther investigation, Nick and Catherine discover that the woman, Sandra Mullins, may have ties to Walter Gordon, the man who kidnapped Nick.

Grissom and his team investigate the shooting death of a young man at a lavish party for a millionaire. Las Vegas’s most influential citizens, including Sam Braun, become suspects.

In a CSI first, a crime will be shown from the killer’s perspective. The CSIs investigate two deaths, both linked to the same suspect. As the evidence starts to overlap, the CSI team begins to move in on the murderer.

A woman’s bald, branded and emaciated body is discovered dumped in the desert. The investigation soon reveals that the victim is the estranged daughter of Grissom’s one-time friend Lady Heather. The probe also reveals that one of the dead woman’s eyeballs isn’t her own and belongs instead to a convicted sex offender. When Grissom confronts Lady Heather, she isn’t too cooperative, but later she provides Grissom with some astonishing evidence.

The CSI team explores the case of a man found stuffed down the chimney of a previous suspect’s home. The CSIs determine that the body they have found was burned before it was dumped down the chimney, leading them to believe the murder was pre-meditated. During the processing of the home, Catherine and Warrick realize that this is the same address of an unsolved homicide of a young female teenager from a year ago, and re-open the investigation.

A camera crew from a reality series follows the CSI team during the first 48 hours of an investigation involving an upscale real estate agent found dead in her glamorous high-rise apartment. The cameras reveal the intricacies of how the CSIs piece together the case, but also delve into how each member of the team deals differently with the emotional and physical demands of their work.

When the body of a young girl is found in a high school, the CSIs are shocked when a twelve year-old classmate confesses to the savage murder. But the CSIs are led to believe that the girl is covering for her brother, so they turn to the evidence to cast some light on which sibling committed the brutal murder. However, the evidence leads them to think that a completely different scheme led to the girl’s murder.

episode 19.A psychic is murdered in her own shop after predicting her own death.The team investigates the death of a psychic who "saw" her own death while performing a reading for two other women. Greg reveals a family secret to Grissom but Grissom believes that science will be what solves the case..

The CSIs are sent to the scene when three teenagers are murdered during the promotion of a rapper's new album. The team find themselves in a world of rappers where artists will use any means necessary, including murder, to get to the top. They soon suspect that Drops, J-Lady (both rappers), or Marcus, an auto dealer, will lead them to the answers they're looking for.

A wealthy defense attorney is murdered at her son’s wedding. The case seems to be going fine until all the evidence and Nick’s car are stolen, compromising the investigation. The team assume that the car and evidence robberies are connected, but when they uncover new evidence, the team is able to piece the crime together.

The CSIs work to find the real story behind the death of a high-stakes gambler and known ladies man. As the case unfolds, they soon find that the victim may have been an unwilling participant to one of his own fantasies, which was created for him to live his dream weekend. The evidence starts to reveal that once his fantasy clashed with reality, things became deadly.

The suspect in a murder investigation leads the CSI crew on a chase through one of Las Vegas’s busiest casinos. After taking a hostage, the man locks himself in a guest room, and the CSIs have to rush to uncover if the man worked alone or not. When their time begins to wind down, one of the CSIs decides to risk their life to negotiate the safe return of the hostage.

In the aftermath of the shooting, the CSI team holds vigil near the bedside of their teammate who may not survive. Meanwhile, the CSIs investigate the scene of a man who was decapitated by a train. After examining the evidence, they discover that the accident was really a cover up for another murder.